First CHOice® LG Medium Plus w.o. HT
First CHOice® products are chemically defined (CD) and protein-free, optimized for the recombinant protein expression with Chinese Hamster Ovary (CHO) cells. All products are produced under GMP compliant conditions.
All First CHOice® products are animal and human component free (ADCF) and designed to boost productivity during bioprocessing. By adjusting the feed rate and selection of the right First CHOice® products, a maximum productivity and optimal product quality can be achieved. All products are suitable for biomanufacturing biological products using CHO-GS, CHO-K1, CHO-S or CHO-DG44.
First CHOice® LG Medium Plus w.o. HT is free from hypoxanthine and thymidine (HT). This medium is specifically designed to reduce the levels of galactosylated N-glycan species in manufacturing processes. A well-matched glycan profile is of particular interest in the development of biosimilars. It has been formulated for highly productive cell lines that grow to high peak cell densities and require a substantial supply of essential nutrients.
First CHOice® LG Medium Plus w.o. HT can be used as a stand-alone medium or blended with First CHOice® Medium w.o. HT or First CHOice® Medium Plus w.o. HT to modulate galactosylation to the desired level. This medium is free of hypoxanthine and thymidine (HT) and can be used for both cell banking and routine cultivation. For productivity screening or manufacturing, the medium can be supplemented with hypoxanthine and thymidine (HT) to optimize productivity.
For further details, please refer to the application note.
Product | Catalog number | Package size | Storage | Shelf life |
---|---|---|---|---|
First CHOice® LG Medium Plus w.o. HT | Liquid: F250002W | 1 L | 2-8°C, protect from light | Expiry date on request* |
Powder: F240002X | 5L | 2-8°C, protect from light, dry environment | Expiry date on request* |
* Stability studies are ongoing for a targeted shelf life of 36 months and data is continuously updated. Current expiry date can be provided on request or please refer to the product label.
For further questions or any technical or scientific support, please contact us:
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Web: www.ugabiopharma.com
Phone: +49 3302 / 2024900