CHO Prime® Media & Feeds

CHO Prime® – Precision in Cell Culture.
Control Over Quality.

More than a Medium: An Adaptive Technology Platform

CHO Prime® is a next-generation, GMP-compliant, adaptive media platform designed to maximise productivity while giving you precise control over critical quality attributes, particularly glycosylation.

Built for production of biologics and biosimilars, CHO Prime® combines chemically defined, animal component free formulations with intelligent media design to deliver performance without compromise.

CHO Prime® Platform enables:

  • Maximisation of growth, viability and productivity
  • Targeted media adjustment to control galactosylation
  • Diminishing metabolic stress and prevention of lactate and ammonium accumulation

The outcome is not just strong performance, but reproducible, controllable product quality batch after batch.

Titer Old Generation Medium & Feeds CHO Prime® Medium & Feeds

Defined. Robust. Manufacturing-Ready.

CHO Prime® Products are:

  • Chemically defined and protein-free
  • Free from animal- and human-derived components (ADCF)
  • Manufactured under GMP-compliant conditions
  • Optimised for high-producing cell lines reaching elevated peak cell densities

CHO Prime® LG Medium w.o. HT

Precise Glycan Modulation for Biosimilar Development

At the core of the platform is CHO Prime® LG Medium w.o. HT.

Specifically developed to reduce galactosylated N-glycan species during manufacturing. It enables closer alignment with originator glycan profiles, a critical success factor in biosimilar development.

CHO Prime® and CHO Prime® LG can be used as stand-alone media or blended to precisely finetune glycosylation levels. This flexibility allows you to balance productivity and glycan control in your development strategy.

Originator's N-glycan profile Elevated galactosylation profile Reduced galactosylation profile Adjusted galactosylation profile
Originator
CHO Prime® 100%
CHO Prime® LG 100%
CHO Prime® 20%: CHO Prime® LG 80%

Flexibility for Development and Manufacturing

CHO Prime® products are available as:

  • Powder formulations
  • Ready-to-use liquid media for R&D purposes

Suitable for CHO-GS, CHO-K1, CHO-S and CHO-DG44 cell lines from screening through to GMP commercial production.

Why CHO Prime®?

With CHO Prime®, you benefit from:

  • Higher productivity
  • Diminished stress metabolite formation
  • Adjustable, well-controlled glycan profiles
  • Chemically defined, GMP-compliant formulations
  • A platform approach that actively modulates product quality

Prime your CHO cells with CHO Prime® Media and Feeds

Order your free test kit now! We tailor the test kit to your specific requirements. Once we receive your request, we’ll get in touch with you to coordinate the details directly.